HCG and TestosteronePenile growth is under androgenic control. Human chorionic gonadotropin hCG has a stimulatory effect on testicular steroidogenesis and penile growth. The purpose of this study was to evaluate the effect of hCG treatment on the gonadal response and penile growth in male idiopathic hypogonadotrophic hypogonadism IHH presenting with micropenis. A total of 20 IHH patients who met the criteria for micropenis were included in hcg and testosterone study. Basic laboratory and hormonal indexes including hcg and testosterone testosterone and LH levelspenis length hcg and testosterone and stretchedand testicular volume were measured before and 24 weeks after hCG treatment. Tablets for menstrual pain patients' mean age was Hdg mean serum testosterone level was significantly increased after hCG treatment baseline, 2, 4, 12, and 24 weeks:
Human Chorionic Gonadotropin (HCG) and Testosterone Therapy - Elite Men's Guide
Testosterone replacement therapy TRT suppresses the natural production of testosterone by the testes. It also reduces sperm production. In most men, it reduces sperm production to levels below what is necessary for fertility. As a result, most men on testosterone therapy are infertile.
While this side effect may not concern certain men, men looking to conceive a child or remain fertile must be aware of this potential side effect of TRT. The body controls the amount of testosterone produced through a feedback mechanism.
When levels are low, chemicals signals released by the hypothalamus and pituitary gland stimulate the testes to produce testosterone. The hypothalamus releases gonadotropin releasing hormone GnRH. Exogenous testosterone taken during testosterone therapy tells the testes not produce more testosterone. Consequently, it inhibits testosterone production by the testes. Since sperm production requires high levels of testosterone within the testes and testosterone therapy suppresses testosterone production by the testes, testosterone therapy reduces sperm production.
During testosterone therapy, the amount of testosterone in the body is normal, but the amount of testosterone within the testes is below normal. Men looking to maintain fertility during testosterone therapy may discuss adding human chorionic gonadotropin to their TRT regimen with their physician.
In men, HCG stimulates the testes to produce testosterone. This testosterone promotes sperm production because intratesticular testosterone testosterone within the testes is necessary for sperm production.
In addition to helping to maintain fertility, HCG may also restore testicular size. As a note, these guidelines are not specifically for men on testosterone therapy.
Therapy with HCG is generally begun at 1, to 2, IU injected intramuscularly two to three times a week. Both testosterone levels and sperm counts should be monitored monthly. Two studies with men specifically on testosterone replacement therapy show that IUs every other day also maintains normal sperm production.
HCG alone can often restore sperm production. As a note, it is imperative that the female partner undergoes assessment for optimal fertility before or concurrently with consideration of therapy in the man. Unlike testosterone, which is a single molecule, human chorionic gonadotropin is a peptide. More specifically, it is a long string of molecules known as amino acids.
Typically HCG comes in the form of a powder in a sterile ampule to prolong its shelf life. When stored at room temperature, unmixed peptides can be kept for approximately 60 days, but reconstituted peptides must be used within 48 hours. When stored in a refrigerator between 35 and 45 degrees Fahrenheit, unmixed peptides can be stored for 18 months, whereas mixed peptides must be used within two months.
Ideally, it should be stored in the refrigerator between 35 and 45 degrees Fahrenheit and kept separate from food and beverages to avoid any cross contamination risk. Unmixed HCG may be frozen one time. Mixed peptides should not be frozen. When frozen, unmixed peptides can be kept for approximately 24 months. Once reconstituted with bacteriostatic water, HCG is given as an injection intramuscularly or subcutaneously under the skin in the fat layer.
Intramuscular injections are typically given in either the glutes, quadriceps, or deltoids. Subcutaneously injections are typically given under the skin in the abdomen. J Clin Endrocrinol and Metab. Concomitant intramuscular human chorionic gonadotropin preserves spermatogenesis in men undergoing testosterone replacement therapy. Annual Review of Biochemistry 50 1: Retrieved 9 December Effects of chronic testosterone administration in normal men: J Clin Endocrinol Metab. American association of clinical endocrinologists medical guidelines for clinical practice for the evaluation and treatment of hypogonadism in adult male patients— update.
Stimulation of spermatogenesis by gonadotropins in men with hypogonadotropic hypogonadism. N Engl J Med. Mulhall JP, Hsiao W. Stimulation of sperm production by human luteinizing hormone in gonadotropin-suppressed normal men. Related Article s Testosterone Gel Testosterone gel delivers a steady dose of testosterone through daily skin applications. These gels are a relatively convenient and effective method of administering testosterone replacement In recent years, testosterone replacement therapy TRT for low testosterone has gained widespread interest from aging men and acceptance from the medical community.
Where Is Testosterone Produced? Testosterone is the principal male sex hormone and anabolic steroid. Testosterone Replacement Therapy for Low Testosterone In recent years, testosterone replacement therapy TRT for low testosterone has gained widespread interest from aging men and acceptance from the medical community.
Where Is It Produced?