HCG for Weight LossTake a "natural" hormone the body makes during pregnancy -- and lose a lot of weight? That's the promise that's turned the hCG Diet -- named after that human chorionic gonadotropin pills -- into a craze that just won't quit. Here's what hhuman science says: Any super-low-cal diet steroid shot first trimester result in weight loss. Most studies have found that human chorionic gonadotropin pills stands for human chorionic gonadotropin has nothing to do with it. None of this is approved by the FDA lills weight loss.
Review of hCG for Weight Loss: Injections and Drops
Homeopathic preparations of hCG do not contain significant amount of the active ingredient, and clinical trials have not been conducted to provide evidence for effect.
Recommendations for dosing for indications other than those approved for hCG cannot be made because evidence to support efficacy is lacking. Precocious puberty, prostatic carcinoma or other androgen-dependent neoplasia, prior allergic reaction to chorionic gonadotropin, and pregnancy. Arterial thromboembolism, headache, irritability and other CNS symptoms, genitourinary effects, and hypersensitivity have been reported.
Defects of forelimbs and the CNS, as well as alterations in sex ratio, have been reported in mice on combined gonadotropin and hCG regimens.
No mutagenic effect has been clearly established in humans. In the s, the endocrinologist Dr. Albert Simeons promoted the use of hCG together with an ultra-low calorie diet calories per day as a weight loss strategy in which the body would preferentially burn stored fat from the stomach, hips, and thighs without causing undesirable loss of muscle tissue, hunger, or irritability.
Following the publication of trials refuting its efficacy and including adverse events, the use of hCG fell out of favor. In the US Food and Drug Administration required labeling and advertising of hCG to state that there was no evidence of efficacy in weight reduction. It is produced by the developing embryo after conception and later by the placenta. The action of hCG is virtually identical to that of pituitary luteinizing hormone, although hCG appears to have a small degree of follicle-stimulating hormone activity as well.
It stimulates production of gonadal steroid hormones by stimulating the testis to produce androgens and the corpus luteum of the ovary to produce progesterone. Animal studies are lacking for the use of hCG in obesity, and based on evidence from clinical trials, would now be redundant. A meta-analysis of clinical trials conducted up to found no evidence of effect for hCG in weight loss, redistribution of fat, or sense of hunger or well-being, beyond that resulting from caloric restriction.
Recommendations for dosing for indications other than those approved for HhCG cannot be made as evidence to support efficacy is lacking.
Trials used units of hCG daily for 6 days out of 7 over a 6-week period for weight reduction. Bioavailability of the injection is greater with intravenous delivery than with subcutaneous delivery. It is not known whether chorionic gonadotropin is excreted in human milk.
Known adverse reactions include arterial thromboembolism, CNS symptoms eg, headache, irritability, restlessness, depression, fatigue, aggressive behavior , and genitourinary and hypersensitivity effects, as well as local effects from the injection eg, pain, edema.
The transmission of hepatitis that was historically associated with the use of jet injectors in clinics was resolved by use of single-use disposable syringes. The dose of gonadotropins used was intended to induce superovulation. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. Pregnyl , Novarel , Ovidrel. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records.
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