A drug notorious for giving users the munchies can in fact help moderate blood sugar levels, waist size, and body mass index (BMI). “Ours is the first study to investigate the relationship between marijuana use and fasting insulin, glucose, and insulin resistance.”. Am J Med. Jul;(7) doi: /es3.info Epub May The impact of marijuana use on glucose, insulin, and insulin. OBJECTIVE We examined if chronic cannabis smoking is associated with hepatic steatosis, insulin resistance, reduced β-cell function, or dyslipidemia in healthy.
Insulin Marijuana and
Using marijuana can help prevent you from accumulating belly fat in the first place, which has positive implications for diabetes and cardiovascular health. This impacts functions and sensations ranging from sleep to hunger to mood to perception of pain. In , Autoimmunity published a study best summarized by its title: While promising, this research deals strictly with mice, and has yet to be translated into practical applications for the treatment of diabetes in humans.
However, while a Cannabis-based drug for diabetes may still be on the horizon, we do have evidence that marijuana can improve, in human subjects, diabetes-related neuropathic pain chronic pain caused by nerve damage.
You can see some examples for yourself in my article about medical studies on Cannabis for diabetic neuropathy. If your quality of life is being negatively impacted by diabetes, diabetic neuropathy, or diabetes-related glaucoma, you may be a good candidate for medical Cannabis in Massachusetts. Tishler at to start discussing the health benefits of medical marijuana in a private consultation.
We partner with some of the companies that sell these products, which means Healthline UK and our partners may receive a portion of revenues if you make a purchase using a link s above. Article last updated by Yvette Brazier on Thu 9 August Visit our Diabetes category page for the latest news on this subject, or sign up to our newsletter to receive the latest updates on Diabetes. All references are available in the References tab.
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American Journal of Epidemiology, 8 , — Metabolic effects of chronic cannabis smoking. Diabetes Care, 36 8 , — The impact of marijuana use on glucose, insulin, and insulin resistance among US adults. The American Journal of Medicine, 7 , — European Journal of Pain, 18 7 , 99— Efficacy of inhaled cannabis on painful diabetic neuropathy [Abstract].
The Journal of Pain, 16 7 , — Marijuana and the developing brain. What is medical marijuana? MNT is the registered trade mark of Healthline Media. Any medical information published on this website is not intended as a substitute for informed medical advice and you should not take any action before consulting with a healthcare professional. Privacy Terms Ad policy Careers. This page was printed from: Get the most out of Medical News Today. Subscribe to our Newsletter to recieve: Professionally-verified articles Daily or weekly updates Content custom-tailored to your needs Create an account.
Sign in Log in with your Medical News Today account to create or edit your custom homepage, catch-up on your opinions notifications and set your newsletter preferences. Register for a free account Sign up for a free Medical News Today account to customize your medical and health news experiences. Register take the tour. Scientists are looking into ways in which substances in marijuana might help treat a range of conditions.
Everything you need to know about marijuana cannabis. Use in medication, some of the chemicals present in marijuana might relieve some of the symptoms of diabetes. Hemp oil may help relieve neuropathic pain in people with diabetes. This was true even when the whole plant had lower doses of the active components. CBD combination, although larger, multicentre trials are required to confirm this.
Animal data discussed below suggest that cannabinoids that activate the CB 2 receptor could also help reduce diabetic-related pain, although this has yet to be tested in humans. One other study has investigated cannabinoid-based medicine in diabetes, published in , which investigated tetrahydrocannabivarin THCV and CBD alone or in combination.
This small, double blinded, randomised controlled trial showed that THCV alone 5 mg twice daily decreases blood glucose levels, but CBD mg twice daily had no effect on various markers of diabetes.
THCV is an interesting compound because it has also been shown to improve insulin sensitivity , reduce eating and cause weight loss in animal studies, suggesting further work should be carried out with this compound in diabetic patients.
In addition to the clinical trials above, much research is currently being conducting in the laboratory in cell, tissue and animal studies to further investigate whether novel cannabinoid-based medicines could be useful in the treatment of diabetes.
Since , there have been many studies published showing that CBD treatment improves many aspects of diabetes and its complications in animal models. In rat and mouse models of type 1 diabetes, CBD reduces the incidence and progression of the disease, reduces pain and temperature sensitivity, reduces cardiac heart damage , reduces inflammation at the retina , and reduces pancreatic inflammation , protecting the islet of Langerhans, where insulin is produced.
In rat models of type 2 diabetes, CBD also improves vascular function. In cells exposed to high glucose levels, CBD reduces the oxidative stress and inflammatory response. This evidence all suggests that CBD might be useful in treating both type 1 and 2 diabetes, although the only clinical trial to date did not find any effect of 12 weeks treatment with CBD mg, twice daily in type 2 diabetic patients. However, comparing this dose of CBD against those which have shown that CBD is effective in animal studies, suggest that the dose of CBD used in this clinical trial was potentially too low and a dose-escalation study is required to test higher doses for comparison, epileptic patients take up to 1 g of CBD daily.
As mentioned, activating the CB 1 receptor with THC human trials or various synthetic compounds animal studies reduces pain and heat sensitivity in diabetic rats.
This can also be achieved by increasing endogenous cannabinoid tone by inhibiting the breakdown of endocannabinoids or their transport. Increasing the levels of endocannabinoids allows them to interact with the CB 1 receptor. Drugs that inhibit endocannabinoid breakdown are being developed clinically and may be available in the future for pain management.
The other main target for cannabinoids in the body is called the CB 2 receptor which has an important role in the immune system. CB 2 activation has also been shown to have beneficial effects in animal models of diabetes.
CB 2 agonists improve insulin sensitivity , reduce cardiac damage , pain , inflammation and kidney damage in animal models diabetes. CB 2 agonists have yet to be trialled in humans in diabetes. As well as CB 1 and CB 2 , cannabinoids act at orphan receptors in the body. These are receptors in the body where we are not sure yet what the chemical is that binds to the receptor.
The impact of marijuana use on glucose, insulin, and insulin resistance among US adults.
What are the medicinal properties of marijuana, or cannabis, and does using A study of people with non-insulin-treated type 2 diabetes. A concern that chronic cannabis users may be curious about, is whether or not cannabis use affects insulin sensitivity. There is not a large. In a study from Harvard Medical School of the health records of 4, people, marijuana users had lower fasting insulin levels and less.