5 Health Benefits of CBD Oils by Canabo Medical Inc. Cannabidiol's While this article is far from an exhaustive list, it does highlight just a few. The body of research on cannabidiol, CBD oil benefits, THC, and other The list of CBD oil benefits and health concerns treatable by CBD is so long because .. Moskowitz MD, personal communication with the authors, February 2, Here, learn more about CBD oil and its uses, benefits, and risks. We also A full list of states that have CBD-specific laws is available here.
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CBD can be extracted from the cannabis plant. CBD is also made synthetically. CBD is produced in pill form, as well as in sprays, tinctures, and inhalers. How does CBD work? We know that CBD interacts with many different receptors, proteins, and other chemicals in the brain.
These interactions create changes in the activity of neurotransmitters, hormones, and other cells throughout the brain and body. This system is involved in regulating many physiological processes, including mood, pain perception, appetite, and cognitive functions. According to a growing body of research, CBD may play a role in the growth of new brain cells, a process known as neurogenesis. CBD is also widely recognized as having anti-oxidant and anti-inflammatory abilities, which make CBD a promising therapy for a wide range of conditions, from neurological disorders to autoimmune diseases to chronic pain and depression.
For sleep CBD has the ability to reduce anxiety, which can be helpful in reducing sleep difficulties and improving sleep quality. CBD may increase overall sleep amounts, and improve insomnia, according to research. CBD has been shown to reduce insomnia in people who suffer from chronic pain. In smaller doses, CBD stimulates alertness and reduces daytime sleepiness, which is important for daytime performance and for the strength and consistency of the sleep-wake cycle. REM behavior disorder is a condition that causes people to act out physically during dreaming and REM sleep.
This immobilization keeps sleepers from reacting physically to their dreams. For depression and anxiety Cannabis has been used for centuries to treat nerves and anxiety, as well as other mood problems. CBD may help to improve both depression and anxiety, at least in part through its interactions with serotonin receptors in the brain.
Research shows that CBD can reduce both mental and physical symptoms of anxiety. A study of CBD given to people before a public-speaking event indicates that CBD can help reduce stress—this and other research has shown that CBD can be an effective treatment for social anxiety.
CBD has been recognized as having anti-psychotic effects. CBD appears to reduce the psychotic symptoms of schizophrenia, and may offer a significant new treatment for this and other mental disorders. For epilepsy One of the most promising uses for CBD is as a treatment for epilepsy.
Scientists have recognized for many years the anti-seizure capabilities of CBD. Recently, CBD has been shown effective in people whose epileptic seizures are resistant to other treatments. One study demonstrated CBD could reduce by 40 percent the number of cigarettes consumed by smokers trying to quit. For neuroprotection and neurodegenerative disease CBD is showing real promise as a compound that can contribute to protecting the brain, thanks to its anti-oxidant and anti-inflammatory abilities.
Scientists are investigating its role in neurogenesis and its ability to help the brain heal from injury, and as a treatment for neurodegenerative disease. Research suggests that CBD may help to reduce brain damage from stroke or other neurological injury. For cancer CBD is being examined closely for its possible role in cancer treatment, on number of different fronts.
It can be effective in reducing pain and nausea in cancer patients. CBD can also stimulate appetite. Always consult your doctor before you begin taking a supplement or make any changes to your existing medication and supplement routine. This is not medical advice, but it is information you can use as a conversation-starter with your physician at your next appointment.
CBD dosing The following doses are based on amounts that have been investigated in scientific studies. In general, it is recommended that users begin with the smallest suggested dose, and gradually increase until it has an effect. A range of doses from 10mg to mg and higher amounts has been studied in scientific research, for sleep problems, anxiety, depression, stress, and other conditions.
People with the following conditions should consult with a physician before using a CBD supplement:. It is recommended that women who are pregnant or breast feeding not use CBD. Effects may include increasing or decreasing sleepiness and drowsiness, interfering with the effectiveness of the medications or supplements, and interfering with the condition that is being treated by the medication or supplement.
These are lists of commonly used medications and supplements that have scientifically identified interactions with CBD. People who take these or any other medications and supplements should consult with a physician before beginning to use CBD. Many commonly used medications are changed or broken down by the liver. Consult with your physician before using CBD if you are taking medication of any kind.
Interactions with other supplements: CBD can increase sleepiness and drowsiness. When CBD is used in combination with other herbs or supplements that promote sleepiness, you may become excessively sleepy. Some of the herbs and supplements used for sleep include: Rich in CBD, cannabis has been used for centuries to fight illness, improve sleep, and lower anxiety. Today, our understanding of the potential benefits of CBD is growing by leaps and bounds—more and more, CBD is seen as a powerful disease-fighting agent.
Alvarez, FJ et al. Neuroprotective effects of the nonpsychoactive cannabinoid in hypoxic-ischemic newborn piglets. Pediatric research, 64 6: Ashton, CH et al.
Cannabinoids in bipolar affective disorder: Journal of psychopharmacology, 19 3: Bakas, T et al. Bradford, Alina , May Cannabidiol as an emergent therapeutic strategy for lessening the impact of inflammation on oxidative stress. Free radical biology and medicine, 51 5: Boychuk, DG, et al. The effectiveness of cannabinoids in the management of chronic nonmalignant neuropathic pain: Hypnotic and antiepileptic effects of cannabidiol. Journal of clinical pharmacology, 21 Suppl: Chagas, MH et al.
Journal of clinical pharmacy and therapeutics, 39 5: Cunha, JM et al. Chronic administration of cannabidiol to healthy volunteers and epileptic patients. Neural basis of anxiolytic effects of cannabidiol CBD in generalized social anxiety disorder: Journal of psychopharmacology, 25 1: Frontiers in Pharmacology, 7: Elikotil, J et al. The Analgesic Potential of Cannabinoids. Journal of Opioid Management, 5 6: Guindon, J and AG Hohmann. The endocannabinoid system and pain. Always start with the micro dose to test sensitivity and go up as needed within the dosing range, before going to the next, until symptoms subside.
The micro to standard dose is usually recommended to treat stress and anxiety with CBD. For relief of immediate symptoms, as in a panic or anxiety attack, vaporizing or smoking work well. The medication lasts one to three hours, whereas most ingested products, including CBD oil, take thirty to sixty minutes before taking effect and last six to eight hours.
Herbal vaporizers that use the whole plant are also an effective delivery method. Sublingual sprays or tinctures taken as liquid drops take effect quickly and last longer than inhaled products. The Cannabis Health Index CHI is an evidence-based scoring system for cannabis in general, not just CBD oil effects and its effectiveness on various health issues based on currently available research data. Using this rubric and based on eleven studies, cannabis rated in the possible-to-probable range of efficacy for treatment of anxiety.
Elixinol Organic High Potency CBD Capsules Elixinol offers a highly concentrated, high-potency, organic whole-hemp plant CBD oil , which is naturally extracted with carbon dioxide and free of all synthetics and chemicals.
Whole-hemp plant extracts contain synergistic compounds that are believed to enhance the effectiveness and benefits of CBD. Clinical depression is a serious mood disorder characterized by persistent sadness and loss of interest, sometimes leading to decreased appetite and energy and suicidal thoughts.
Commonly used pharmaceuticals for depression often target serotonin, a chemical messenger that is believed to act as a mood stabilizer. The neural network of the endocannabinoid system works similarly to the way that serotonin, dopamine, and other systems do, and, according to some research, cannabinoids have an effect on serotonin levels.
Whereas a low dose of THC increases serotonin, high doses cause a decrease that could worsen the condition. CBD products with a ratio of Specifically, products made with Valentine X or Electra 4 are more energizing, helping relieve depression. When low energy is an issue, sativa or other stimulating strains can be helpful for improving energy and focus when THC can be tolerated.
Varieties that are high in the terpene limonene are recommended for mood elevation. Always start with the micro dose to test sensitivity and go up as needed within the dosing range before going to the next, until symptoms subside. The micro to standard dose is usually recommended to treat depression. Vaporized or smoked cannabis is recommended for relief of immediate symptoms, or a boost in dosage, and it can also be useful for sleep issues.
The Cannabis Health Index CHI is an evidence-based scoring system for cannabis in general, not just CBD effects and its effectiveness on various health issues based on currently available research data.
Using this rubric and based on twenty-one studies, cannabis rated in the possible-to-probable range of efficacy for treatment of depression. Research in called for clinical trials to look into the effectiveness of cannabinoids for bipolar disorder manic depression.
It also works on the GABA-glutamate system and the hypothalamic-pituitary-adrenal axis. Its main role is restoring balance through inhibition when levels are too high and enhancement when they are too low. This is the most likely reason phytocannabinoids in general and CBD specifically are able to regulate depression and anxiety. The scientific inquiry into cannabis over the past several decades has confirmed that it is an effective and safe analgesic for many kinds of pain.
Of all the reasons that people use CBD today, pain is the most common. The same can be said of cannabis in general. In the United States, over seventy million people suffer from chronic pain, which is defined as experiencing over one hundred days per year of pain. Physicians differentiate between neuropathic usually chronic and nociceptive pains usually time-limited , and cannabis works on most neuropathic and many nociceptive types of pain. A number of studies have demonstrated that the endocannabinoid system is both centrally and peripherally involved in the processing of pain signals.
Cannabinoids can be used along with opioid medications, and a number of studies have demonstrated that they can reduce the amount of opioids needed, lessen the buildup of tolerance, and reduce the severity of withdrawal. It is suggested that patients work with a health care practitioner experienced in recommending CBD oil or medicinal cannabis so that dosage and delivery methods can be developed and fine-tuned on an individual basis. Oral CBD products with a ratio of Most discussions of treating pain with CBD suggest that finding the right dosage is critical.
Always start with the micro dose to test sensitivity and go up as needed within the dosing range by body weight until symptoms subside. If CBD-dominant products alone are not enough to treat a particular case, products with a higher ratio of THC are sometimes recommended to better manage pain. For day use, more stimulating, sativa varieties with higher concentrations of myrcene could be added to the formula.
In general, for pain, and especially for evening and nighttime, indica strains are favored for their relaxing, sedative effect. A person without experience with THC should use caution and titrate slowly up to higher doses. Research as well as patient feedback have indicated that, in general, a ratio of 4: THC is the most effective for both neuropathic and inflammatory pain.
Each individual is different, however—for some, a 1: Chemotypes high in beta-caryophyllene, myrcene, and linalool provide additional pain relief and increase the effectiveness of other cannabinoids for analgesia. For relief of immediate symptoms, as in a flare-up of pain, vaporizing or smoking work well. The medication effect is immediate and lasts one to three hours, whereas most ingested products take thirty to sixty minutes before taking effect faster on an empty stomach and last six to eight hours.
Sublingual sprays or tinctures taken as liquid drops also take effect quickly and last longer than inhaled products. When pain is localized, topical products can be applied. Topicals affect the cells near application and through several layers of tissue but do not cross the blood-brain barrier and are, therefore, not psychoactive.
The skin has the highest amount and concentration of CB2 receptors in the body. Considering all of the studies together, which number over forty for various types of pain , CBD and cannabis are shown to have a rating of likely probable efficacy. It is one of the best-substantiated medical uses of cannabinoids.
Sativex, a cannabis plant—derived oromucosal spray containing equal proportions of THC and CBD, has been approved in a number of countries for use to treat specific types of pain. Numerous randomized clinical trials have demonstrated the safety and efficacy of Sativex for treatment of central and peripheral neuropathic pain, rheumatoid arthritis, and cancer pain.
A study showed that CBD and CBC stimulated descending pain-blocking pathways in the nervous system and caused analgesia by interacting with several target proteins involved in nociceptive control.
Sleep Disorders Insomnia, Sleep Apnea Cannabis and sleep have a complex relationship that is only beginning to be understood by science.
In general, for most people, indica strains are more relaxing and effective for sleep disorders, whereas sativa strains are more stimulating and tend to keep people awake.
Several studies conducted between and demonstrated the variable effect of different cannabinoids on sleep. Another study found CBD to be wake-inducing for most subjects, though some reported better sleep a few hours after taking it. However, a significant number of people find THC, even indica strains, will make the mind more active. For these people, CBD oil can benefit them and tends to work well, providing the relaxation and calm for the mental as well as the physical body.
For these people, CBD taken at nighttime as part of a bedtime regime produces a restful sleep, not the alertness produced in the daytime. This bidirectional effect of CBD is the result of balancing the endocannabinoid system. In relation to sleep apnea, a animal study observed the ability of THC to restore respiratory stability by modulating serotonin signaling and reducing spontaneous sleep-disordered breathing. It is suggested that patients work with a health care practitioner experienced in recommending CBD or medicinal cannabis so that dosage and delivery methods can be developed and fine-tuned on an individual basis.
As mentioned previously, while CBD-dominant products help some people sleep, in others it promotes wakefulness. These tend to be high in myrcene and linalool, a terpene shared with lavender and known to be effective for relaxation. Cannabis combinations with ratios of 1: THC can be used when patients want to reduce psychoactivity. Oral consumption is recommended as it usually lasts the whole night. The micro to standard dose is usually recommended to treat insomnia and sleep apnea.
When relaxing indica strains are used with higher THC levels, a dose of 5—10 mg is usually sufficient. Other people find they need larger doses, such as 15—40 mg. CBD taken as a tincture or edible will aid in a restful six to seven hours of sleep. This type of disorder varies widely from one patient to the next. Often, one needs to perform some experimental research and try strains of different CBD: For immediate medicinal effects, vaporizing or smoking work well.
This can be helpful for either initial sleep onset or for wakefulness in the middle of a rest period but only lasts one to three hours. The medication effect is immediate, whereas most ingested products take thirty to sixty minutes before taking effect faster on an empty stomach and last six to eight hours.
Vaporizers that use a cartridge filled with the CO2 concentrate are convenient and highly effective, and these are available in various ratios of CBD to THC.
Understanding CBD: The calming and sleep promoting benefits of cannabidiol
15, -- A compound found in the cannabis plant is not harmful, has health benefits, and does not have abuse potential, experts at the World Health Organization . In the U.S., CBD is a Schedule 1 controlled substance. The health benefits of CBD oil are being studied by world-class researchers We analyzed and summarized 17 of the best CBD studies of While this is not a comprehensive list, it does highlight some of the critical. Geneva, November Page 2. 39th ECDD () Agenda item Cannabidiol (CBD). Page 2 of 27 .. Listing on the WHO Model List of Essential Medicines. . In humans, CBD exhibits no effects indicative of any abuse or.