The benefits of CBD; Where does CBD come from? It has been used since antiquity for its sturdy fiber, for oils, and for medicinal purposes. However, it has. Q: Will I get "high" if I use Hemp oil or CBD oil? A: NO! All of our hemp products are 3rd party tested to ensure there is no THC present. THC is. "Joe Bob who starts up a CBD company could say whatever the hell he but those results come mostly from animal studies, experts said.
From? Come What Does It and – Oil Is Where CBD It
These invaluable properties of THC have given rise to the use of marijuana for legal medical purposes. There have been certain studies that found statistically significant correlations between long-term use of THC and certain psychiatric disorders , including schizophrenia, depression, and psychosis.
However, we must note here that in scientific studies such as these, correlation does not imply causation; that is, the usage of THC might be linked to psychiatric disorders without necessarily being that root cause of them. Much like lighters are linked to smoking, but possession of a lighter does not necessarily mean you are a smoker. The CBD vs THC debate is something that often crops up in the circles of cannabis users, and it mainly stems from misinformation that surrounds these substances.
Science is an evolving process and it pays to stay up to date, especially on new industries like CBD. First off, you should know the basics of what CBD is. Simply put, cannabinoids are naturally occurring compounds found in the cannabis plant. Together they are responsible for the benefits and drawbacks to medical marijuana and industrial hemp-based products. But there are also several other types of cannabinoids you should know about too.
There are also cannabinoids manufactured via chemical reactions in laboratories, known as synthetic cannabinoids. So now that you understand what a cannabinoid is, how does CBD work with your body? As we just stated, the endocannabinoid system includes a number of specialized cell receptors in the brain and in various other organs throughout the body. These receptors fall into two types: CB1 receptors are found mainly in the brain but also in the liver, kidneys, and lungs , while CB2 receptors are found mainly in the immune system.
As we discussed above, there are several types of cannabinoids. Even within phytocannabinoids, there are wide ranges of compounds and effects that we are still learning about. Other cannabinoids, like CBD, have fewer direct effects on the endocannabinoid system keep this in mind as you read the next section. Cannabinoids represent a diverse class of chemical compounds that can be very different from each other.
For example, arachidonoylethanolamine AEA is produced within the body and is thought to regulate several functions. For example, CB1 receptors send signals that regulate senses, while cannabinoids that interact with CB2 receptors can at the same time affect gastrointestinal response and peripheral nervous system sensitivity.
Also, since people often take numerous different cannabinoids together for example, using medical marijuana , it is hard to attribute specific effects to specific cannabinoids.
In addition, some cannabinoids interact synergistically, producing unique effects that are not found when using them individually.
However, CBD does this and produces many other effects without directly interacting with the cannabinoid receptors. At first, scientists thought there was a third type of CB receptor just for Cannabidiol, but the answer was far more interesting and revealing.
The indirect interactions of CBD with the endocannabinoid system has many effects, some of which surprised scientists and are still being researched.
However, scientists are still unclear about how some effects of Cannabidiol are actually occurring. The most possible explanation is via the hypothetical GPR55 receptor, or through more indirect and synergistic effects that still await discovery. Contrary to how most cannabinoids function, CBD interacts very mildly with the cannabinoid receptors themselves and instead either helps other cannabinoids to be better absorbed or stops the effects of whatever makes the receptors work less effectively.
The endocannabinoid system is closely interconnected with the nervous and immune system. You may have heard some people say that marijuana and hemp are exactly the same, while others swear they are different. The debate of hemp vs marijuana is fueled by the confusion and misinformation that surround the cannabis plant. In this article, we will dispel several myths and shed light on the differences between industrial hemp and marijuana. As you may know, industrial hemp and marijuana come from the same genus of flowering plant— cannabis.
This means that there may be multiple types of the cannabis plant, which are all cannabis but have remarkable differences. Cannabis sativa is the most common strain of cannabis. It has been cultivated throughout history for a number of purposes, including the production of seed oil, food, hemp fiber for clothes and rope , medicine, and even recreation. Cannabis ruderalis is a species native to Russia that flowers earlier and is able to withstand harsher conditions than Cannabis sativa and Cannabis indica.
It is the hardiest of the three, but it is relatively poor in terms of cannabinoids as ruderalis has a lower THC content than either sativa or indica. Cannabis indica was first discovered in India and is a cannabis species that is described as shorter and bushier than sativa. Problems with botanical taxonomy have led some scientists to still doubt the existence of Cannabis indica as a distinct species of cannabis. However, since man has been cultivating cannabis and especially Cannabis sativa for thousands of years, the effects of artificial selections have led to several different types of cannabis even within the same species, depending on the purpose the cannabis was cultivated for.
Cannabis has been cultivated by humans, for a variety of purposes, since antiquity. So it comes as no surprise that there are several different species and even different varieties within the species, depending on the purpose the plants were bred for. Through artificial selection, different species of cannabis have different properties—some have been used for medicinal purposes, others as food, and others to create clothes, ropes, and other items. Industrial hemp is produced by strains of Cannabis sativa that have been cultivated to produce minimal levels of THC and are instead artificially selected and bred to grow taller and sturdier.
This is done to enable the plant to be used effectively in the production of hemp oil, wax, resin, hemp seed food, animal feed, fuel, cloth, rope, and more. Industrial hemp is exclusively made from Cannabis sativa. Medical marijuana is produced mainly from variants of Cannabis sativa that have been selectively bred to maximize their concentration in cannabinoids. Cannabis ruderalis is almost exclusively grown due to its naturally occurring very small quantities of THC.
The major and arguably the only difference between industrial hemp and medical marijuana is that industrial hemp is exclusively made from Cannabis sativa that was specifically bred to produce the lowest concentrations of THC possible. Stimulation of CB 1 in the brain increases dopamine , which counteracts pain.
Just as importantly, these same chemical substances reduce inflammation , the driving force behind pain , which allows healing to occur. CBD and other cannabinoids also reduce pain by affecting endorphins, the feel-good chemicals we naturally produce to suppress pain. Unlike opioids heroin, narcotics , which mimic endorphins and ultimately suppress natural endorphins, cannabinoids modulate endorphins.
This means, in effect, that CBD and cannabinoids increase natural endorphins. So instead of causing dependence and addiction like opioids, CBD and cannabinoids do the opposite — so much so that CBD has proven valuable for countering narcotic and cocaine addiction. From a medicinal standpoint, the fact that CBD has the potential to relieve pain without causing euphoria, intoxication, or addiction makes it an intriguing therapeutic option — it has high potential for being at least a partial solution to the current opioid epidemic.
CBD and other chemical substances in hemp flower-bud extracts are strong immune system modulators. This means they control inflammation throughout the body, and also fine-tune the immune system for optimal performance. The wide range of benefits associated with cannabis have garnered interest for use in cancer therapy. Research suggests that cannabinoids, including CBD, may have anti-tumor effects. While this is not enough to define cannabis as a treatment for cancer, it does make it attractive as a complement to other therapies , for both reducing symptoms and possibly enhancing the effects of anticancer drugs.
Terpenes and the wide spectrum of other chemical compounds found in hemp flower-bud extracts provide potent anti-inflammatory and antioxidant properties. This is a common source of confusion. Many people see hemp oil on grocery store shelves and assume or wonder if it contains CBD and other cannabinoids. The hemp oil you might see on grocery store shelves is made by cold pressing hemp seeds.
While hemp oil is a healthful option for a salad dressing, it has no medicinal value by itself. Cannabinoids, including CBD in hemp and THC in marijuana, are most highly concentrated in the flower buds, not the seeds.
These chemical components of the plant must be extracted from the flower buds to be useful. For medicinal use, cannabinoids are extracted from hemp and concentrated into a thick oil that, when ingested, elevates blood levels of cannabinoids for a more sustained period of time. CBD oil from hemp contains CBD and other cannabinoids, along with terpenes and other chemical components. The most common method, chemical extraction uses alcohol or hexane as solvents. The solvent is dried off, leaving the dense oil — and possibly harmful residual solvents — behind.
A newer method, CO 2 extraction is done without using chemical solvents. Instead, it uses carbon dioxide to extract the full range of chemical components from the flower buds and then distill them into dense CBD oil.
Also sometimes called thermal extraction, vapor distillation uses hot air to safely vaporize the full spectrum of chemical components at high concentration from the buds, and then the vapor is distilled into CBD oil. This method also activates the cannabinoids by removing an extra carboxyl ring from their molecular chain a chemical reaction called decarboxylation , enabling them to interact directly with CB receptors for maximal medicinal value.
I believe vapor distillation is the best method for obtaining the full range of activated chemical compounds from the cannabis plant.
This method preserves the terpenes, which are beneficial on their own, and also enhance the properties of CBD via the entourage effect. The upsides of lipid-based extraction are that the fat helps make the CBD more bioavailable easy to absorb , and there are no harsh solvents used. Condensed CBD oil can be taken as a thick paste, but this is the least pleasant option. More commonly, the CBD oil is mixed with a carrier oil, such as hemp oil or coconut oil, to a specific concentration of CBD.
The distinctive taste — which comes from the terpenes and not the cannabinoids — is often masked with chocolate, mint, or other flavorings. It typically comes in a small bottle with a dropper to administer the oil mixture.
The best way to take CBD oil mixed with a carrier oil to a specific concentration is to place a few drops or dropperfuls under your tongue for 15 seconds to access the sublingual gland.
There, the CBD is absorbed directly into the bloodstream called sublingual consumption or administration for the fastest acting effects. Another method is to take a few drops or dropperfuls orally, swish the liquid around in your mouth, and then swallow it.
CBD oil mixed with a carrier oil can also be taken as soft-gel capsules to avoid any taste, but absorption is only through the intestinal tract.
The average dose range is mg of CBD, one to three times per day, though much higher doses of mg sometimes required to control pain are equally well tolerated. Some people will notice benefit at the lower end of the dose range, but most people will need mg to notice any effects. Because different products provide different concentrations of CBD, the packaging usually states how much CBD is in the entire bottle as opposed to the amount in a certain number of drops or dropperfuls, so measuring can be a little tricky.
A dropperful of the medium grade product mg of CBD per fluid ounce will deliver about 15 mg of CBD — a good starting dose. And a dropperful of a high concentration product mg CBD per fluid ounce will provide about 50 mg of CBD per dropperful. CBD oil is also available as soft gel capsules. With these, the mg quantity of CBD should be designated per capsule. Because some of the chemical compounds in capsules are lost during digestion, you may find you need to take a little more to experience the benefits.
As with any medicinal herb, start at a low dose and gradually build up to a higher dose as you get used to the effects of the substance. Most people notice benefits almost immediately, but some experts suggest that full benefit does not occur until after a couple of weeks of consecutive use. CBD isolate which is CBD alone acts very differently in the body than a spectrum of hemp chemical components.
Here are some quick definitions:. The cannabis plant naturally generates cannabinoids, terpenes, and other chemical compounds to serve different functions in the plant.
These functions include regulatory properties, potent antioxidants, and protection from microbes and insects. Any creature that consumes the chemicals from the plant gains these same benefits. When you consume CBD oil, you gain the benefits of all those chemical substances in natural synergy. For that reason, you get full benefit at a dose range of mg. CBD isolate is limited to that single chemical messenger. The synergy provided by the full spectrum of chemicals in CBD oil is lost.
This is likely why clinical studies using purified CBD require very high doses, in the range of mg of CBD several times daily, to see a benefit. When CBD is formally legalized at the national level, prescription drugs providing high doses of purified CBD will become available several are already in the pipeline. Reported side effects of hemp oil with CBD are generally mild and uncommon and can include tiredness, loose stools, and mild changes in appetite and weight either increased or decreased.
Both hemp oil with CBD hemp flower-bud extracts and purified CBD CBD isolate have been shown in both animal and human clinical trials to be remarkably safe and well tolerated. Prolonged use is not associated with an increased risk of side effects.
In research studies , up to mg of purified CBD per day has been used to address various medical illnesses without reported harmful effects including changes in heart rate, blood pressure, temperature, oxygen and carbon dioxide levels, electrolyte balance, gastrointestinal function, psychomotor functions, or sleep cycles. Prolonged use at high doses has not shown potential for abuse of CBD.
In fact, a clinical study published in found that recreational polydrug users did not show abuse potential with use of CBD. Long-term studies have not evaluated potential changes in hormonal balance or long-term adverse changes in liver function, though prolonged use of CBD enhances metabolism of certain drugs.
Stopping CBD oil suddenly has not been associated with withdrawal effects. While the cost of CBD oil products is presently high, it will likely come down dramatically after CBD and hemp are legal by federal standards — but prices will still vary widely.
Reputable companies selling CBD oil products will state the CBD concentration and extraction methods on the bottle or website. Typically, the concentration is stated as milligrams mg of CBD per fluid ounce though some products standardize mg of CBD to milliliters ml. The benefit comes from the amount of CBD consumed, not the amount of oil. To calculate the cost per milligram of CBD, simply divide the dollar amount of the product by the total milligrams of CBD in the bottle.
As for extraction methods, remember that vapor distillation and CO2 extraction are preferred. Lipid-based extractions will likely fall in the middle price-wise. The highest quality cannabis is grown indoors , so quality standards can be controlled. Use of clean water and organic methods of farming that are free of pesticide use and unnatural fertilizers are, of course, preferred.
With outdoor-farmed cannabis, quality standards and potency are not as easily controlled. Taste can be a sign of value, too. Poor quality oils will have a very unpleasant chemical taste, and they can cause significant burning to mouth tissues.
A good quality product should be smooth and not cause significant burning. Interestingly, the best quality products are associated with a distinct cannabis taste, indicating that the full spectrum of chemical components with trace levels of THC are present. Even in high doses, CBD oil will not cause euphoria or impair coordination, balance, or motor functions.
Use of CBD oil is associated with improved sense of well-being, but not an exaggerated feeling of well-being. Use of CBD oil has never been associated with hallucinations or abnormal mental activity. Creams and salves for musculoskeletal discomfort generally contain very small amounts of CBD that are absorbed through the skin.
Many of these products do provide significant benefit, however, but the benefit is likely derived from other aspects of CBD — especially terpenes from cannabis and essential oils, thanks to their anti-inflammatory properties. Though CBD will likely become a highly promoted ingredient in beauty products, it is unclear whether the concentration of CBD present in these products will provide a benefit.
There is near zero potential of becoming habituated to hemp CBD products. It should be noted that recreational use of marijuana high THC, low CBD cannabis does result in dependence but different from narcotics or alcohol, and not as debilitating. Chronic use of THC may be associated with atrophy in certain areas of the brain and reduction of certain cognitive functions at this point, studies are not conclusive.
Interestingly, studies have shown that taking CBD oil regularly can restore areas of the brain that have become atrophied in marijuana abusers. There have been no reports of anyone overdosing on cannabis. This sets even recreational use of cannabis widely apart from narcotics and alcohol, both of which can cause severe respiratory depression and death at excessive doses.
Excessive doses of hemp, and more especially, marijuana, may make you very agitated and feel terrible, but there are no known deaths from cannabis overdose. Many food and beverage companies are already taking advantage of the growing CBD trend and adding CBD to food and beverage products, though the practice is not approved by the FDA.
Using CBD in defined doses for medicinal purposes is one thing, but putting it in food and beverages is something entirely different. Someone may wind up getting CBD from multiple products, and so their daily dose could vary significantly. Taking a standardized dose of CBD oil daily as a recognized medicinal is a very different thing from taking uncontrolled doses of CBD isolate daily infused artificially into food and beverage products, and the long term risk may be very different — no one really knows for sure.
Like most herbs, cannabis does have some antimicrobial and immune-boosting properties, but it is not as strong an antimicrobial as many other herbs. There are many better herbal choices for overcoming chronic Lyme disease and similar conditions related to chronic infections with stealth microbes such as fibromyalgia and chronic fatigue syndrome.
The bottom line is, CBD oil is a good option for controlling symptoms associated with Lyme disease, fibromyalgia, and other chronic illnesses, but it should be combined with other antimicrobial and immunomodulating herbs for optimal benefit. CBD oil is best used intermittently to treat symptoms of pain or anxiety, or used chronically only until symptoms gradually resolve, and then discontinued.
The story around CBD will continue to change and evolve once hemp is legalized and as the industry continues to grow and advance.
The Science Behind CBD Oil: Everything You Need to Know
The cannabis oil works by relaxing the mind and body, and generating a lower energy level, it will be easier for you to get your heart rate down. Cannabidiol (CBD) is a phytocannabinoid discovered in It is one of some identified It may be supplied as CBD oil containing only CBD as the active ingredient (no added THC or terpenes), .. Act. In the rules were changed so that anyone wanting to use it could go to the Health Ministry for approval. Hemp oil or hempseed oil is obtained by pressing hemp seeds. Cold pressed, unrefined hemp oil is dark to clear light green in color, with a nutty flavour. The darker the color, the grassier the flavour. It should not be confused with hash oil, a tetrahydrocannabinol-containing oil.